An, Qi published the artcileStructure analysis of polysaccharides purified from Cyclocarya paliurus with DEAE-Cellulose and its antioxidant activity in RAW264.7 cells, Application In Synthesis of 59-23-4, the main research area is Cyclocarya polysaccharide CPPD macrophage cell viability antioxidant; Antioxidant; Cyclocarya paliurus; Polysaccharide; Structural analysis.
CPP was isolated from Cyclocarya paliurus (C. paliurus) and CPP-D was purified from CPP with a further step by DEAE-Cellulose. In this study, the structure and antioxidant activities of these two polysaccharides were investigated. The mol. weight of CPP was determined as 1.15 à 105 Da and the monosaccharides of it were Rha, Ara, Xyl, Man, Glc, Gal in a molar ratio of 0.021:0.237:0.020:0.036:0.454:0.231, while the mol. weight of CPP-D was 9.1 à 103 Da and the monosaccharides of it were Man, Glc, Gal in a molar ratio of 0.235:0.677:0.088. CPP-D consisted of three structural residues â?- β-D-Glc-(1â? â?,6)- β-D-Man-(1â?and â?)- β-D-Gal. These structures were characterized by SEM, FT-IR, GC-MS, HPGPC, and NMR. The antioxidant assay in RAW264.7 cell showed that both CPP and CPP-D promoted cell viability and antioxidant activity, which decreased the content of MDA and increased the activity of SOD, T-AOC, CAT (P < .05). As a result, CPP-D isolated by DEAE-Cellulose didn't reduce the antioxidant activity of C. paliurus polysaccharide and could enhance the cell viability. International Journal of Biological Macromolecules published new progress about Antioxidants. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Application In Synthesis of 59-23-4.
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