Zhang, Jianzhi published the artcileProduction and characterization of exopolysaccharides from Chlorella zofingiensis and Chlorella vulgaris with anti-colorectal cancer activity, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is Chlorella exopolysaccharide colon cancer antioxidant anticancer agent; Antitumor; Chlorella vulgaris; Chlorella zofingiensis; Exopolysaccharide; Physicochemical property.
The production, physicochem. characteristics, antioxidant and antitumor activities of partial purified exopolysaccharides from Chlorella zofingiensis, Chlorella vulgaris were investigated. The final exopolysaccharides productions were 208.4, 364.3 mg/L and the average mol. weights were 2.66×104, 1.88×104 Da, resp. Monosaccharide anal. indicating that these exopolysaccharides consisted of 10 or 11 different kinds of sugars and derivatives, resp. Addnl., they exhibited obvious radical scavenging activities on DPPH and hydroxyl radicals, which reached to 59.6-71.5% and 44.5-70.4%, resp. Moreover, the antitumor effects were studied using human colon cancer cell lines HCT8. The results showed that they had significant antitumor effects considering the inhibitory effects on cell viabilities (28.3-18.0% on HCT8, resp.). Thus, these exopolysaccharides from microalgae species are worth further investigating as alternative potential antitumor agents.
International Journal of Biological Macromolecules published new progress about Antioxidants. 59-23-4 belongs to class alcohols-buliding-blocks, name is (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal, and the molecular formula is C6H12O6, Recommanded Product: (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal.
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