Panda, Surajit published the artcileEfficient α-Alkylation of Arylacetonitriles with Secondary Alcohols Catalyzed by a Phosphine-Free Air-Stable Iridium(III) Complex, Category: alcohols-buliding-blocks, the main research area is iridium complex catalyzed alkylation arylacetonitrile secondary alc.
A well-defined and readily available air-stable dimeric iridium(III) complex catalyzed α-alkylation of arylacetonitriles using secondary alcs. with the liberation of water as the only byproduct is reported. The α-alkylations were efficiently performed at 120°C under solvent-free conditions with very low (0.1-0.01 mol %) catalyst loading. Various secondary alcs. including cyclic and acyclic alcs. and a wide variety of arylacetonitriles bearing different functional groups were converted into the corresponding α-alkylated products in good yields. Mechanistic study revealed that the reaction proceeds via alc. activation by metal-ligand cooperation with the formation of reactive iridium-hydride species.
Journal of Organic Chemistry published new progress about Acetonitriles Role: RCT (Reactant), RACT (Reactant or Reagent). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Category: alcohols-buliding-blocks.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts