Hang, Zhaojun’s team published research in Tetrahedron Letters in 2022-01-05 | CAS: 22483-09-6

Tetrahedron Letters published new progress about Cyanamides Role: SPN (Synthetic Preparation), PREP (Preparation). 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, HPLC of Formula: 22483-09-6.

Hang, Zhaojun published the artcileA practical method for N-cyanation of secondary amines and sulfonamides, HPLC of Formula: 22483-09-6, the main research area is cyanamide preparation; secondary amine sulfonamide CBX cyanation alk condition.

Cyanamides are an important class of mols. This work describes a facile synthesis of disubstituted cyanamides. Here, readily accessible 1-cyano-1,2-benziodoxol-3-(1H)-one (CBX) was applied as a stable electrophilic cyanation reagent. Diverse secondary amines were effectively cyanated. Moreover, secondary sulfonamides proved to be suitable substrates and were readily converted to N-alkyl(aryl)-N-arylsulfonyl-cyanamides, as the significant building blocks of the organic transformation.

Tetrahedron Letters published new progress about Cyanamides Role: SPN (Synthetic Preparation), PREP (Preparation). 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, HPLC of Formula: 22483-09-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts