Chen, Wei-Jin published the artcileElectrochemical synthesis of 1,2,3-trisubstituted pyrroles from β-dicarbonyl compounds, aldehydes and amines via radical addition reaction, Quality Control of 22483-09-6, the main research area is pyrrole preparation electrochem; dicarbonyl compound aldehyde amine three component radical addition reaction.
An efficient electrochem. synthesis of 1,2,3-trisubstituted pyrroles I (R1 = n-Pr, Bn, cyclohexyl, etc.; R2 = H, Ph, Bn, i-Pr, etc.; R3 = Me, OMe, OEt, OPr, Ph) was developed by one-pot three-component reaction of β-dicarbonyl compounds, R3C(O)CH2C(O)CH3 aldehydes R2CH2CHO with amines R1NH2. The target products could be obtained in good to excellent yields. The investigations indicate that β-enamino ketone is a key intermediate in this transformation and the reaction mechanism may involve a radical addition reaction pathway.
Tetrahedron Letters published new progress about 1,3-Dicarbonyl compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, Quality Control of 22483-09-6.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts