Krieg, Sara-Cathrin published the artcileStereoselective Synthesis of 2-Oxyenamides, Computed Properties of 22483-09-6, the main research area is acylated oxyenamide diastereoselective preparation DFT; acyl chloride aminoacetaldehyde dimethyl acetal acylation; sulfonylated oxyenamide diastereoselective preparation DFT; sulfonyl chloride aminoacetaldehyde dimethyl acetal sulfonylation.
An improved route for highly stereoselective synthesis of (Z)-2-oxyenamides I [R = cyclohexyl, 2-furyl, 4-BrC6H4, etc.; R1 = Me, 2-thienyl, 4-MeOC6H4, etc.] was reported. The desired products could be accessed in only three steps from aminoacetaldehyde di-Me acetal as common, readily available building block in a highly modular fashion. The improved procedure had been applied to synthesis of various acylated and sufonylated oxyenamides. Mechanistic and theor. studies provided a conclusive rationale for observed stereoselectivities.
European Journal of Organic Chemistry published new progress about Acetals Role: RCT (Reactant), RACT (Reactant or Reagent) (aminoacetaldehyde). 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, Computed Properties of 22483-09-6.
Referemce:
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Alcohols – Chemistry LibreTexts