Wang, Siyu published the artcileIron-catalyzed borylation and silylation of unactivated tertiary, secondary, and primary alkyl chlorides, Application In Synthesis of 124-76-5, the main research area is tertiary secondary primary alkyl chloride iron catalysis borylation silylation.
Herein, we describe an iron-catalyzed borylation and silylation of unactivated alkyl chlorides, delivering the tertiary, secondary, and primary alkylboronic esters, and secondary, primary alkylsilanes with high efficiency. This protocol exhibits broad substrate scope and good functional group compatibility, allowing the efficient late-stage borylation of biorelevant compounds, thus offering an excellent platform in drug discovery and development. Preliminary mechanistic studies suggest that an alkyl radical was involved in this catalytic system.
CCS Chemistry published new progress about Alkylsilanes Role: PEP (Physical, Engineering or Chemical Process), PROC (Process). 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Application In Synthesis of 124-76-5.
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