Yasukata, Tatsuro published the artcilePractical Synthetic Method for the Preparation of Pyrone Diesters: An Efficient Synthetic Route for the Synthesis of Dolutegravir Sodium, Name: 2,2-Dimethoxyethanamine, the main research area is pyrone diester dolutegravir sodium synthesis.
A highly efficient and practical synthetic method for the preparation of pyrone diesters was established. The pyrone diester 3c (I) can be prepared from readily available starting materials on a multihundred gram scale. The pyrone diester 3c can easily be converted to dolutegravir sodium (II.Na). The synthetic route demonstrated herein provides an efficient and atom-economical synthetic method for preparing this potent anti-HIV agent.
Organic Process Research & Development published new progress about Atom economy. 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, Name: 2,2-Dimethoxyethanamine.
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