Neopentylic rearrangement of 2,2-disubstituted-1,3-propanediols in acid was written by Mazet, Michel. And the article was included in Bulletin de la Societe Chimique de France in 1969.Application In Synthesis of 2-Butyl-2-ethylpropane-1,3-diol The following contents are mentioned in the article:
The dehydration and substituent migration rates (Yvernault, Th. and Mazet, M., 1969), of 2,2-dihydrocarbyl-1,3-propanediols were studied in H2SO4. The reaction occurred by a synchronic ionization-migration mechanism. The substituents had a steric effect. The rates increased with the mol. weight of one of the substituents, and were higher for aryl, as compared to alkyl groups. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4Application In Synthesis of 2-Butyl-2-ethylpropane-1,3-diol).
2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application In Synthesis of 2-Butyl-2-ethylpropane-1,3-diol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts