Development of chiral catalysts by asymmetric activation for highly enantioselective diethylzinc addition to imines was written by Zhang, Hai-Le;Liu, Hua;Cui, Xin;Mi, Ai-Qiao;Jiang, Yao-Zhong;Gong, Liu-Zhu. And the article was included in Synlett in 2005.Reference of 851615-07-1 The following contents are mentioned in the article:
Based on the asym. activation concept, a library of chiral zinc complexes formed in situ by the combination of diimines derived from chiral 1,2-diphenyl-ethanene-1,2-diamine, BINOL derivatives, and diethylzinc are evaluated in the asym. addition of diethylzinc to N-acylimines. In the presence of 10 mol% catalyst I high enantioselectivities and yields were provided for a wide range of aromatic imines in 1,2-dichloroethane at -25 °C. This study involved multiple reactions and reactants, such as (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1Reference of 851615-07-1).
(R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Reference of 851615-07-1
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts