Rhodamine B derivatives-modified upconversion nanoparticles as a fluorescent turn-off-on sensor for the highly sensitive detection of Cu2+ and pyrophosphate was written by Meng, Zhipeng;Wu, Suli;Zhong, Linghua;Zeng, Min;Sun, Xiaoqian;Li, Lu;Zhang, Shufen. And the article was included in RSC Advances in 2018.Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:
Rhodamine B derivatives (RBP)-modified UCNPs (UCNPs@mSiO2-RBP) were developed as a fluorescent turn-off-on sensor based on FRET and IFE to detect Cu2+ and pyrophosphate (PPi) with a wide linear response range (0-10 μM for Cu2+ and 5-35 μM for PPi, much wider than that reported previously) and high sensibility (117 nM for Cu2+ and 70 nM for PPi). The MTT experiments and the bioimaging experiments show its promising prospect in tissue imaging. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts