Thorpe-Ingold hypothesis of valency deviation. Intramolecular H-bonding in 2-substituted propane-1,3-diols was written by Schleyer, Paul von Rague. And the article was included in Journal of the American Chemical Society in 1961.Quality Control of 2-Butyl-2-ethylpropane-1,3-diol The following contents are mentioned in the article:
The Thorpe-Ingold hypothesis of valency deviation was examined by determination of the spectral shifts near 3 μ due to intramol. H-bonding in propane-1,3-diols. Results obtained indicated C-C-C angles appreciably larger than 109.5° in cyclopropane-1,1-dimethanol and propane-1,3-diol and slightly spread angles in cyclobutene-1,1-dimethanol and 2-monoalkyl substituted propane-1,3-diols. The method was not applicable to 1,3-diols with bulky substituents because of adverse steric effects. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4Quality Control of 2-Butyl-2-ethylpropane-1,3-diol).
2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Quality Control of 2-Butyl-2-ethylpropane-1,3-diol
Referemce:
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