Rapid Synthesis of 3,3′ Bis-Arylated BINOL Derivatives Using a C-H Borylation in Situ Suzuki-Miyaura Coupling Sequence was written by Ahmed, Ijaz;Clark, Daniel A.. And the article was included in Organic Letters in 2014.Product Details of 851615-07-1 The following contents are mentioned in the article:
The increased interest in BINOL derived catalysts for asym. transformations has encouraged us to disclose a rapid and scalable method of preparing 3,3′ bis-arylated BINOL derivatives 1 using a one-pot CH borylation/Suzuki-Miyaura coupling sequence. The use of an aldehyde additive was found to be crucial to the success of this in situ tandem approach. This method was applied to the preparation of 10 BINOL derivatives, each completed within 24 h. Notably, this approach requires only a single purification step. This study involved multiple reactions and reactants, such as (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1Product Details of 851615-07-1).
(R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Product Details of 851615-07-1
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts