Aubineau, Thomas’s team published research in Synlett in 2021-03-31 | CAS: 22483-09-6

Synlett published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, Name: 2,2-Dimethoxyethanamine.

Aubineau, Thomas published the artcileIron-Catalyzed Diastereoselective Synthesis of Disubstituted Morpholines via C-O or C-N Bond Formation, Name: 2,2-Dimethoxyethanamine, the main research area is hydroxybutenyl hydroxyethyl methylbenzenesulfonamide iron chloride catalyst diastereoselective heterocyclization; tosylmorpholine preparation green chem; butenyhydroxy oxyethyl methylbenzenesulfonamide iron chloride catalyst diastereoselective heterocyclization; styryl tosylmorpholine preparation green chem.

The diastereoselective synthesis of 2,6- and 3,5-disubstituted morpholines was achieved from 1,2-amino ethers and 1,2-hydroxy amines substituted by an allylic alc. using an iron(III) catalyst. The morpholines were obtained either by C-O or C-N bond formation. A plausible mechanism was suggested, involving a thermodn. equilibrium to explain the formation of the cis diastereoisomer as the major product.

Synlett published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, Name: 2,2-Dimethoxyethanamine.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts