Kong, Ying-Ying published the artcileIridium-Catalyzed α-Alkylation of Arylacetonitriles Using Secondary and Primary Alcohols, SDS of cas: 584-02-1, the main research area is alkylated arylacetonitrile green preparation; alc arylacetonitrile alpha alkylation iridium catalyst.
In the presence of NaOtBu, [Cp*IrCl2]2-catalyzed reaction of arylacetonitriles with alcs. was performed to yield α-monoalkylation products of arylacetonitriles such as I [R1 = (CH2)2CH3, (CH2)4CH3, CH2(CH2)2Ph, etc .; R2 = H, Ph; R1 = R2 = Me, Et; R1R2 = CH2(CH2)2CH2, CH2(CH2)3CH2, CH2(CH2)5CH2, etc.; Ar = Ph, 4-PhC6H4, 2-naphthyl, etc.]. The catalyst and conditions also suited for the α-monoalkylation of arylacetonitriles with primary alcs.
Asian Journal of Organic Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, SDS of cas: 584-02-1.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts