Tkalec, Ziga published the artcileLC-HRMS based method for suspect/non-targeted screening for biomarkers of chemical exposure in human urine, Category: alcohols-buliding-blocks, the publication is Chemosphere (2022), 134550, database is CAplus and MEDLINE.
Every day we are exposed to a cocktail of anthropogenic compounds many of which are biol. active and capable of inducing neg. effects. The simplest way to monitor contaminants in a population is via human biomonitoring (HBM), however conventional targeted approaches require foreknowledge of chems. of concern, often have compound specific extractions and provide information only for those compounds This study developed an extraction process for human biomarkers of interest (BoE) in urine that is less compound specific. Combining this with an ultra-high resolution mass spectrometer capable of operating in full scan, and a suspect and non-targeted anal. (SS/NTA) approach, this method provides a more holistic characterization of human exposure. Sample preparation development was based on enzymically hydrolyzed urine spiked with 34 native standards and extracted by solid-phase extraction (SPE). HRMS data was processed by MzMine2 and 80% of standards were identified in the final data matrix using typical NTA data processing procedures.
Chemosphere published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C11H10N4, Category: alcohols-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts