Woller, Eric K.’s team published research in Biomacromolecules in 2 | CAS: 96345-79-8

Woller, Eric K. published the artcileMannose Functionalization of a Sixth Generation Dendrimer, Recommanded Product: (2R,3S,4S,5S,6R)-2-(Hydroxymethyl)-6-(4-isothiocyanatophenoxy)tetrahydro-2H-pyran-3,4,5-triol, the publication is Biomacromolecules (2001), 2(3), 1052-1054, database is CAplus and MEDLINE.

Saccharide functionalization of fourth through sixth generation PAMAM dendrimers was carried out using a thiourea linkage occurs in high yield (77-92 %) with 85% incorporation of sugar residues. Reaction of 4-isothiocyanatophenyl α-D-mannopyranoside with amine-terminated G(4)-, G(5)-, and G(6)-PAMAMs afforded mannosylated dendrimers. Only a slight excess of the isothiocyanate (≤1.1 equiv/amine) was used. Protection of the mannose hydroxy groups was not necessary as isothiocyanates react selectively with primary amines. Dialysis against a water/ DMSO mixture using a cellulose tube (MW cutoff of 1000 g/mol) afforded the functionalized dendrimers in purified form. A widely applicable MALDI-TOF MS procedure was used for the anal. of the degree of dendrimer surface functionalization achieved.

Biomacromolecules published new progress about 96345-79-8. 96345-79-8 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Gal and Man, name is (2R,3S,4S,5S,6R)-2-(Hydroxymethyl)-6-(4-isothiocyanatophenoxy)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C8H5F3O2S, Recommanded Product: (2R,3S,4S,5S,6R)-2-(Hydroxymethyl)-6-(4-isothiocyanatophenoxy)tetrahydro-2H-pyran-3,4,5-triol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts