Natarajan, P. N. published the artcileSynthesis and pharmacological evaluation of N-alkylamino butanol esters of 3,4,5-trimethoxybenzoic acid as potential hypotensive agents, HPLC of Formula: 4543-95-7, the publication is Canadian Journal of Pharmaceutical Sciences (1973), 8(2), 61-3, database is CAplus.
The title esters I (R = Me, Et, Pr, Me2CH, Bu) were prepared by condensing γ-butyrolactone with RNH2, reducing the resulting HO(CH2)3CONHR with LiAlH4, and esterifying the hydrochlorides of the amines formed with 3,4,5-(MeO)3C6H2COCl in C6H6 at ∼70° under N for 15-20 hr. Evaluation of I, for hypotensive activity in normotensive rats and for central nervous system activity in mice showed that I did not have any reserpine-like activity.
Canadian Journal of Pharmaceutical Sciences published new progress about 4543-95-7. 4543-95-7 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 4-(Butylamino)butan-1-ol, and the molecular formula is C8H19NO, HPLC of Formula: 4543-95-7.
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Alcohols – Chemistry LibreTexts