Wang, Pengxin published the artcileDearomatization-rearomatization strategy of tyrosine for peptide/protein modification through thiol-addition reactions, Computed Properties of 4410-99-5, the publication is Chemical Communications (Cambridge, United Kingdom) (2021), 57(96), 12968-12971, database is CAplus and MEDLINE.
We have developed a dearomatization-rearomatization strategy for the modification of peptides/proteins through a thiol-Michael addition to the electrophilic cyclohexadienone intermediate that is generated in situ via the oxidation of tyrosine. This strategy enriches the conjugation toolbox and has great potential for applications in medicinal chem. and chem. biol.
Chemical Communications (Cambridge, United Kingdom) published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C9H8O4, Computed Properties of 4410-99-5.
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