Chen, Tsun-Ren published the artcileIridium/graphene nanostructured catalyst for the N-alkylation of amines to synthesize nitrogen-containing derivatives and heterocyclic compounds in a green process, Formula: C5H12O2, the publication is RSC Advances (2022), 12(8), 4760-4770, database is CAplus and MEDLINE.
A facile iridium/graphene-catalyzed methodol. providing an efficient synthetic route for C-N bond formation is reported. This catalyst can directly promote the formation of C-N bonds, without pre-activation steps, and without solvents, alkalis and other additives. This protocol provides a direct N-alkylation of amines using a variety of primary and secondary alcs. with good selectivity and excellent yields. Charmingly, the use of diols resulted in intermol. cyclization of amines, and such products are privileged structures in biol. active compounds Two examples illustrate the advantages of this catalyst in organic synthesis: the tandem catalysis to synthesize hydroxyzine, and the intermol. cyclization to synthesize cyclizine. Water is the only byproduct, which makes this catalytic process sustainable and environmentally friendly.
RSC Advances published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Formula: C5H12O2.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts