Huang, Wenbo published the artcileSynthesis of Multisubstituted Pyrroles from Enolizable Aldehydes and Primary Amines Promoted by Iodine, Recommanded Product: 4,4-Diethoxybutan-1-amine, the publication is Journal of Organic Chemistry (2019), 84(9), 5655-5666, database is CAplus and MEDLINE.
1,2,4-Trisubstituted pyrroles were synthesized from enolizable aliphatic aldehydes and primary aliphatic amines by using iodine as the dual Lewis acid/mild oxidant. In the presence of 3.0 equiv of TBHP, enolizable α,β-unsaturated aldehyde, for example, cocal reacted with aromatic primary amines to form C2-iodized N-arylpyrroles. An acetal-containing pyrrole was successfully prepared from 4-aminobutyraldehyde di-Et acetal, which can be converted easily to 5,6,7,8-tetrahydroindolizine derivatives
Journal of Organic Chemistry published new progress about 6346-09-4. 6346-09-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Ether, name is 4,4-Diethoxybutan-1-amine, and the molecular formula is C8H19NO2, Recommanded Product: 4,4-Diethoxybutan-1-amine.
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