Hecht, Stephen S.’s team published research in Tetrahedron Letters in | CAS: 4543-95-7

Tetrahedron Letters published new progress about 4543-95-7. 4543-95-7 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 4-(Butylamino)butan-1-ol, and the molecular formula is C8H19NO, HPLC of Formula: 4543-95-7.

Hecht, Stephen S. published the artcileA study of chemical carcinogenesis. II. Synthesis of N-nitrosamino aldehydes, HPLC of Formula: 4543-95-7, the publication is Tetrahedron Letters (1976), 593-6, database is CAplus.

The alcs. RNHCHR1(CH2)3OH (I; R = Pr, Me, PhCH2, R1 = H) were prepared from Cl(CH2)4OH and the corresponding amine; I (R = Me, R1 = 3-pyridyl) was prepared by condensation of Et nicotinate with butyrolactone to give dihydro-3-(3-pyridoyl)-2-(3H)-furanone, which was successively hydrolyzed, decarboxylated, and treated with NaBH3CN and MeNH2. Nitrosation of I with NaNO2 gave RN(N:O)CHR1(CH2)3OH which was oxidized with dicyclohexylcarbodiimide in DMSO to give RN(N:O)CHR1(CH2)2CHO. The aldehydes were mixtures of Z- and E-isomers.

Tetrahedron Letters published new progress about 4543-95-7. 4543-95-7 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 4-(Butylamino)butan-1-ol, and the molecular formula is C8H19NO, HPLC of Formula: 4543-95-7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts