Chatterjee, Maya published the artcileProduction of lactic acid mediated by compressed carbon dioxide on heterogeneous Ni(
Lactic acid is one of the appealing platform mols. in organic synthesis, currently in high demand after the innovation of bio-plastics. The limitations of traditional manufacturing routes (microbial process and chem. synthesis using petroleum resources) directed us to develop economically and environmentally viable catalytic strategies exploring renewable resources to meet the expected demand. In this study, we demonstrated a method of lactic acid synthesis by fixing CO2 as a waste gas into acetaldehyde used as a biobased feedstock on a highly active, recyclable heterogeneous Ni catalyst. The significance of the developed process lies in the transformation of easily available low-cost starting materials to a high-value product without harsh reaction conditions, extra sensitive reagents, and addnl. steps to derive the right starting material or to remove impurities, which is advantageous in terms of sustainability. Moreover, the optimization of different reaction parameters ensures achieving high yields (>80%) and an excellent production rate of 6700μmol g-1 h-1. In addition, the characterization of the catalyst by different spectroscopic techniques suggested an interaction between the substrate and the catalyst, which provides an indication of the possible reaction path, thus a mechanism would be outlined. The successful extension of this process to various aldehydes was possible to produce their corresponding hydroxycarboxylic acid with broad functional group tolerance. Altogether, this methodol. opens up a promising avenue for the production of biochems. from renewable resources, which is a key to develop a sustainable society.
Green Chemistry published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C8H8O3, Application of 2-Hydroxy-2-phenylacetic acid.
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