Botero, David published the artcileComparative study of pyrantel pamoate, bephenium hydroxynaphthoate, and tetrachloroethylene in the treatment of Necator americanus infections, HPLC of Formula: 3818-50-6, the publication is American Journal of Tropical Medicine and Hygiene (1972), 22(1), 45-52, database is CAplus and MEDLINE.
A study of 105 patients with the hookworm N. americanus infections was undertaken to compare the new anthelmintic pyrantel pamoate (I-pamoate) [22204-24-6] and 2 commonly used drugs bephenium hydroxynaphthoate [3818-50-6] and tetrachloroethylene [127-18-4]. I, in a dose of 10 mg/day, orally, for 3 days, had action comparable or superior to the other drugs against the hookworm. In addition, I caused an almost 100% cure rate in patients infected with Ascaris lumbricoides, and caused a slight decrease in egg count in patients infected with Trichuris trichiura. I was tolerated well and no toxic effects were observed by hematol. and biochem. examination
American Journal of Tropical Medicine and Hygiene published new progress about 3818-50-6. 3818-50-6 belongs to alcohols-buliding-blocks, auxiliary class Anti-infection,Antiparasitic, name is N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxy-2-naphthoate, and the molecular formula is C28H29NO4, HPLC of Formula: 3818-50-6.
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