In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 111-46-6, name is 2,2′-Oxybis(ethan-1-ol), the common compound, a new synthetic route is introduced below. SDS of cas: 111-46-6
Diethylene glycol (7.0 g, 66.0 mmol) was dissolved in 10 mL of dichloromethane solution, Et3N (13.3 g, 132.2 mmol) was added, and TsCl (15.1 g, 79.1 mmol) in dichloromethane was added dropwise on ice. .After the completion of the dropwise addition, the mixture was transferred to room temperature and stirred overnight.After adjusting the pH of the solution to 7 with 6 mol/L HCl, 10 mL of water was added, and the mixture was extracted three times with 30 mL of dichloromethane, and the organic phases were combined and dried over anhydrous sodium sulfate.Column chromatography (EA) gave 10 g of a yellow liquid product, yield 60%.
The synthetic route of 111-46-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Zhejiang University of Technology; Zhang Xingxian; He Kailun; Wang Wenbing; Wang Xiaoju; Zheng Xiaoliang; (23 pag.)CN110204532; (2019); A;,
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