Lopez de Laorden, Carlos published the artcileNanostructured Indium Tin Oxide Slides for Small-Molecule Profiling and Imaging Mass Spectrometry of Metabolites by Surface-Assisted Laser Desorption Ionization MS, HPLC of Formula: 85618-21-9, the publication is Analytical Chemistry (Washington, DC, United States) (2015), 87(1), 431-440, database is CAplus and MEDLINE.
Due to their elec. conductivity and optical transparency, slides coated with a thin layer of indium tin oxide (ITO) are the standard substrate for protein imaging mass spectrometry on tissue samples by MALDI-TOF MS. The authors have now studied the radiofrequency magnetron sputtering deposition parameters to prepare ITO thin films on glass substrates with the required nanometric surface structure for their use in the matrix-free imaging of metabolites and small-mol. drugs, without affecting the transparency required for classical histol. The custom-made surfaces were characterized by at. force microscopy, SEM, ellipsometry, UV, and laser desorption ionization MS (LDI-MS) and employed for the LDI-MS-based anal. of glycans and druglike mols., the quantification of lactose in milk by isotopic dilution, and metabolite imaging on mouse brain tissue samples.
Analytical Chemistry (Washington, DC, United States) published new progress about 85618-21-9. 85618-21-9 belongs to alcohols-buliding-blocks, auxiliary class Tetrahydropyran,Chiral,sulfides,Alcohol, name is (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(octylthio)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C14H28O5S, HPLC of Formula: 85618-21-9.
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