Panchale, Wrushali A. published the artcileFirst-order derivative spectrophotometric estimation of gemifloxacin mesylate and ambroxol HCl in tablet dosage form, Category: alcohols-buliding-blocks, the publication is GSC Biological and Pharmaceutical Sciences (2021), 14(2), 29-36, database is CAplus.
Aim of present work was to develop and validate a simple, precise and accurate uv-vis spectrophotometric method for the simultaneous estimation of gemifloxacin mesylate (GEMI) and ambroxol HCl (AMB) in their combined tablet dosage form. The method is based on first-order derivative spectroscopy. For determination of sampling wavelengths, each of GEMI and AMB were scanned in the wavelength range of 200-400 nm in the spectrum mode and sampling wavelengths were selected at 360 nm (zero crossing of GEMI) where AMB showed considerable absorbance and at 221.6 nm (zero crossing of AMB) where GEMI showed considerable absorbance. The linearity was obtained in the concentration range of 32-192μg/mL for GEMI and 7.5-45μg/mL for AMB. The correlation coefficients were found to be 0.9987 and 0.9992 for GEMI and AMB, resp. The method was validated as per ICH guidelines. Mean recoveries were found satisfactory. All the data of validation study was found to be satisfactorily. The proposed method can be applied for simultaneous estimation of both the drugs.
GSC Biological and Pharmaceutical Sciences published new progress about 23828-92-4. 23828-92-4 belongs to alcohols-buliding-blocks, auxiliary class Membrane Transporter/Ion Channel,Sodium Channel, name is trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride, and the molecular formula is C13H19Br2ClN2O, Category: alcohols-buliding-blocks.
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https://en.wikipedia.org/wiki/Alcohol,
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