In Water and under Mild Conditions: α-Alkylation of Ketones with Alcohols by Phase-Transfer-Assisted Borrowing Hydrogen Catalysis was written by Rakers, Lena;Schaefers, Felix;Glorius, Frank. And the article was included in Chemistry – A European Journal in 2018.Related Products of 106-21-8 The following contents are mentioned in the article:
Borrowing hydrogen is a powerful and green technique that allows readily available alcs. to be used as alkylating agents and produces water as the only byproduct. Nevertheless, harsh conditions such as high temperatures and organic solvents are usually required. Herein, we present a strategy to perform the α-alkylation of ketones in aqueous media at mild temperatures by combining borrowing hydrogen with phase-transfer catalysis. A broad scope of Me ketones was functionalized with alkyl and benzyl alcs. in moderate to good yields at 40 °C.The protocol was also highly effective at large scale and room temperature This study involved multiple reactions and reactants, such as 3,7-Dimethyloctan-1-ol (cas: 106-21-8Related Products of 106-21-8).
3,7-Dimethyloctan-1-ol (cas: 106-21-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Related Products of 106-21-8
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts