Sulfamides direct radical-mediated chlorination of aliphatic C-H bonds was written by Short, Melanie A.;Shehata, Mina F.;Sanders, Matthew A.;Roizen, Jennifer L.. And the article was included in Chemical Science in 2020.HPLC of Formula: 106-21-8 The following contents are mentioned in the article:
Herein, sulfamides served as amine surrogates to guide intermol. chlorine-transfer at γ-C(sp3) centers. This unusual position-selectivity arised because accessed sulfamidyl radical intermediates engaged preferentially in otherwise rare 1,6-hydrogen-atom transfer (HAT) processed through seven-membered transition states. The site-selectivity of C-H abstraction could be modulated by adjusting steric and electronic properties of sulfamide nitrogen substituents, an ability that had not been demonstrated with other substrate classes. The disclosed reaction relied on a light-initiated radical chain-propagation mechanism to oxidize C(sp3)-H bonds efficiently. This study involved multiple reactions and reactants, such as 3,7-Dimethyloctan-1-ol (cas: 106-21-8HPLC of Formula: 106-21-8).
3,7-Dimethyloctan-1-ol (cas: 106-21-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.HPLC of Formula: 106-21-8
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts