Helical water-soluble NiII complexes with pyridoxal ligand derivatives: Structural evaluation and interaction with biomacromolecules was written by Mainardi Martins, Francisco;Chaves, Otavio Augusto;Acunha, Thiago V.;Roman, Daiane;Iglesias, Bernardo Almeida;Back, Davi Fernando. And the article was included in Journal of Inorganic Biochemistry in 2021.Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:
This article deals with the synthesis of Schiff-based bis-azomethine-based ligands derived from pyridoxal and aliphatic dihydrazides (L1-L3) and the synthesis of Ni(II) complexes C1-C4. The synthesized complexes had their structures elucidated by monocrystal x-ray diffraction and were characterized by vibrational and absorption spectroscopy. The synthesized ligands have characteristics that gave self-assembly processes, thus, the flexibility or rigidity of the coordination of organic mols. added to the orbitals of the NiII cation gives helical complexes with double helix and a dinuclear Ni(II) complex. Also, compounds was their interactions with CT-DNA and HSA absorption and emission anal. and mol. docking calculations This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Name: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts