A pyridoxal-based dual chemosensor for visual detection of copper ion and ratiometric fluorescent detection of zinc ion was written by Qu, Lijun;Yin, Caixia;Huo, Fangjun;Chao, Jianbin;Zhang, Yongbin;Cheng, Fangqin. And the article was included in Sensors and Actuators, B: Chemical in 2014.Recommanded Product: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:
A pyridoxal-based fluorescein derivative was synthesized by reacting fluorescein hydrazide and pyridoxal hydrochloride in ethanol and characterized by NMR, ESI-MS and X-ray. The optical properties of probe were investigated in methanol: HEPES solution The probe displayed selectivity for Cu2+, which was characterized using UV-visible spectroscopy. Moreover, the process also allowed visual detection of Cu2+ by a colorless to yellow change. In contrast, selectivity toward Zn2+ was determined in the emission spectra showing OFF-ON type fluorescence changes from colorless to green. This represents the first reported pyridoxal-based sensor capable of detecting both Cu2+ and Zn2+ using two different modes. Furthermore, it can be used to bioimaging. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Recommanded Product: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Recommanded Product: 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride
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