Yb(III), Sm(III) and La(III) complexes of a tetradentate pyridoxal Schiff base ligand: Their DNA-binding activity and bio-imaging applications was written by Chakraborty, Moumita;Mondal, Satyajit;Cardin, Christine;Rheingold, Arnold L.;Das Mukhopadhyay, Chitrangada;Kumar Chattopadhyay, Shyamal. And the article was included in Polyhedron in 2020.HPLC of Formula: 65-22-5 The following contents are mentioned in the article:
Yb(III), Sm(III) and La(III) complexes of a tetradentate Schiff base ligand, bis(pyridoxylidene)ethyelenediamine, are reported. Single crystal x-ray structures of the complexes reveal that in all the three complexes the Ln(III) ions are in a distorted dodecahedral geometry with N4O4-coordination environment provided by two coordinated ligands. Fluorescence spectroscopy shows that in the Yb(III) and Sm(III) complexes energy transfer from ligand centered excited state leads to population of an emissive f-f excited state. The complexes bind to ct-DNA, with high binding constant (Kb) comparable to those compounds (like ethydium bromide) which bind by intercalative mode. Cytotoxicity study shows that the complexes have quite low cytotoxicity towards HeLa cells. Further, they exhibited fast response, bright fluorescence and stability at physiol. pH, making them suitable for use in fluorescence bio-imaging. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5HPLC of Formula: 65-22-5).
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.HPLC of Formula: 65-22-5
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts