Structural characterization and thermal behaviour of some azomethine compounds derived from pyridoxal and 4-aminoantipyrine was written by Mezey, Reka-Stefana;Zaharescu, Traian;Lungulescu, Marius Eduard;Marinescu, Virgil;Shova, Sergiu;Rosu, Tudor. And the article was included in Journal of Thermal Analysis and Calorimetry in 2016.Formula: C8H10ClNO3 The following contents are mentioned in the article:
Eight azomethine-type compounds derived from pyridoxal (3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde) and 4-aminoantipyrine, resp., were prepared and thoroughly characterized from structural and thermal perspective. The structures of the compounds were studied based on IR, 1H and 13C NMR spectroscopy and electrospray ionization mass spectrometry. The formation of the azomethine derivatives was confirmed by the occurrence of signals typical for the imine bond. Pyrazolone derivatives feature a high crystallinity, and their structures were resolved by single-crystal X-ray diffraction. The thermal behavior of all the compounds were studied by non-isothermal chemiluminescence in static air atm. at different heating rates. The pattern of the oxidation process was described. Moreover, thermo-gravimetric and differential scanning calorimetry experiments were conducted in order to assess the thermal oxidation stability. The onset oxidation temperatures showed a high thermal stability for all the tested azomethine compounds The crystallinity degree was comparatively evaluated on the basis of melting enthalpy values and discussed in connection with the mol. structure. Pyrazolone derivatives showed the higher thermal stability and crystallinity degree. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Formula: C8H10ClNO3).
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Formula: C8H10ClNO3
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts