Related Products of 100-86-7, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.100-86-7, name is 2-Methyl-1-phenyl-2-propanol, molecular formula is C10H14O, molecular weight is 150.22, as common compound, the synthetic route is as follows.
50mL egg-shaped flask was added N – saccharin trifluoromethylthio group 1 (110mg, 0.39mmol), 2- methyl-3-phenyl propanol (45.0mg, 0.3mmol), 96muL triethylamine (0.69mmol), in dichloromethane (5 mL), at room temperature for 5min.After completion of the reaction, the reaction solution rapidly by about 6 millimeters silica gel column, the column with the amount of methylene chloride and washed twice, and the combined organic liquid, spin dry to give trifluoromethyl – (2-benzyl) isopropyl thio peroxide (62mg, 83% isolated yield).Purity by NMR identified more than 95%.Trifluoromethyl – (2-benzyl-yl) thio-isopropyl peroxy (((2-Methyl-1-phenylpropan-2-YL) Oxy) (trifluoromethyl) sulfane):
Statistics shows that 100-86-7 is playing an increasingly important role. we look forward to future research findings about 2-Methyl-1-phenyl-2-propanol.
Reference:
Patent; Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences; Chen, Qilong; Xu, Chunfa; (25 pag.)CN104945298; (2016); B;,
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