Reference of 27489-62-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 27489-62-9, name is trans-4-Aminocyclohexanol. This compound has unique chemical properties. The synthetic route is as follows.
To a solution of trans-4-aminohexanol (10 g, 87 mmol) and triethylamine (18 mL, 0.13 mol) in dichloromethane (44 mL), di (tert-butyl) dicarbonate (21 g, 96 mmol) was added under cooling on ice. After stirring the obtained solution at room temperature for 6.5 hours, water and 1 N hydrochloric acid were added to the reaction solution, and the obtained solution was extracted with chloroform. The organic layer was dried over anhydrous sodium sulfate and then concentrated under vacuum. The obtained crude product was purified by recrystallization with a mixed solvent of hexane/ethyl acetate, and the precipitated solid was recovered by filtration to obtain the title compound (13 g). 1H-NMR (400 MHz, CDCl3) delta (ppm): 1.12 – 1.21 (2H, m), 1.33 – 1.44 (11H, m), 1.97 – 2.01 (4H, m), 3.40 – 3.43 (1H, m), 3.60 – 3.61 (1H, m), 4.33 – 4.35 (1H, m).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 27489-62-9, trans-4-Aminocyclohexanol.
Reference:
Patent; Toray Industries, Inc.; NISHIO, Yukihiro; KUBOTA, Yuko; YAMAMOTO, Masashi; NISHIMURA, Yutaka; MASUDA, Tomohide; TSUTSUI, Hideyuki; OKIMURA, Keiichi; UDAGAWA, Syuji; KAINO, Mie; MEGURO, Hiroyuki; SEKIYA, Yumiko; (105 pag.)EP3345893; (2018); A1;,
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