Patel, Grishma H. published the artcileRp-hplc method development and validation for simultaneous estimation of efonidipine hydrochloride ethanolate and telmisartan in their synthetic mixture, Recommanded Product: 2-(Benzyl(phenyl)amino)ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate ethanol hydrochloride, the publication is International Journal of Pharmaceutics and Drug Analysis (2021), 9(3), 190-195, database is CAplus.
A Novel, selective, accurate and rapid Reversed Phase High Performance Liquid Chromatog. (RPHPLC) method for the anal. of Efonidipine Hydrochloride Ethanolate and Telmisartan in binary mixture has been developed and validated. The chromatog. system consisted of a Phenomenex Kinetex 5μ C18 Size: 150 * 4.6mm column and the separation was achieved by using ambient temperature with a mobile phase containing mobile Phase Acetonitrile:25mM Phosphate Buffer pH 4.9 (45:55). The samples were monitored at 253 nm for detection at a flow rate of 1.0 mL/min and the retention time was about 7.77 and 4.10 mins for Efonidipine Hydrochloride Ehanolate and Telmisartan resp. The calibration curve was linear over the concentration range 5-30 and 10-60μg/mL for Efonidipine Hydrochloride Ehanolate and Telmisartan resp. The proposed method is accurate in the range of 99.75% – 100.10% recovery and precise (%RSD of intraday variation and % RSD of inter day variation were found to be within the acceptance criteria). Therefore, this method can be used as a more convenient and efficient option for the anal. of Efonidipine Hydrochloride Ehanolate and Telmisartan in Quality control laboratory
International Journal of Pharmaceutics and Drug Analysis published new progress about 111011-76-8. 111011-76-8 belongs to alcohols-buliding-blocks, auxiliary class Membrane Transporter/Ion Channel,Calcium Channel, name is 2-(Benzyl(phenyl)amino)ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate ethanol hydrochloride, and the molecular formula is C36H45ClN3O8P, Recommanded Product: 2-(Benzyl(phenyl)amino)ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate ethanol hydrochloride.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts