Chemical modifications of porous shape memory polymers for enhanced X-ray and MRI visibility was written by Fletcher, Grace K.;Nash, Landon D.;Graul, Lance M.;Jang, Lindy K.;Herting, Scott M.;Wilcox, Matthew D.;Touchet, Tyler J.;Sweatt, Ana Katarina;McDougall, Mary P.;Wright, Steven M.;Maitland, Duncan J.. And the article was included in Molecules in 2020.Product Details of 115-84-4 The following contents are mentioned in the article:
The goal of this work was to develop a shape memory polymer (SMP) foam with visibility under both X-ray and magnetic resonance imaging (MRI) modalities. A porous polymeric material with these properties is desirable in medical device development for applications requiring thermoresponsive tissue scaffolds with clin. imaging capabilities. Dual modality visibility was achieved by chem. incorporating monomers with X-ray visible iodine-motifs and MRI visible monomers with gadolinium content. Phys. and thermomech. characterization showed the effect of increased gadopentetic acid (GPA) on shape memory behavior. Multiple compositions showed brightening effects in pilot, T1-weighted MR imaging. There was a correlation between the polymeric d. and X-ray visibility on expanded and compressed SMP foams. Addnl., extractions and indirect cytocompatibility studies were performed to address toxicity concerns of gadolinium-based contrast agents (GBCAs). This material platform has the potential to be used in a variety of medical devices. This study involved multiple reactions and reactants, such as 2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4Product Details of 115-84-4).
2-Butyl-2-ethylpropane-1,3-diol (cas: 115-84-4) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Product Details of 115-84-4
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