Vodnala, Nagaraju et al. published their research in Journal of Organic Chemistry in 2022 | CAS: 620-92-8

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Quality Control of 4,4′-Methylenediphenol

Lewis Acid-Promoted Typical Friedel-Crafts Reactions Using DMSO as a Carbon Source was written by Vodnala, Nagaraju;Singh, Sanjay;Hazra, Chinmoy Kumar. And the article was included in Journal of Organic Chemistry in 2022.Quality Control of 4,4′-Methylenediphenol The following contents are mentioned in the article:

A mild and efficient synthetic protocol for the synthesis of sym. and unsym. diarylmethanes (DAMs) R1CH2R2 (R1 = 4-methoxyphenyl, 2,4,6-trimethylphenyl, 1H-indol-3-yl, 4-hydroxy-2-oxo-2H-chromen-3-yl, etc.; R2 = 4-hydroxy-3,5-dimethylphenyl, 5-methylfuran-2-yl, 4-amino-3,5-bis(propan-2-yl)phenyl, etc.) was reported. Using DMSO as the C1 source and TMSOTf as the Lewis acid promoter, a series of functionalized sym. and unsym. DAMs was synthesized in high yields. Gratifyingly, DMSO plays a dual role as a solvent and a C1 source and can also be replaced with its deuterated counterpart, DMSO-d6, enabling the incorporation of the -CD2 moiety into the diarylmethane skeleton. The developed approach has been applied to a wide range of substrates having various functional groups, and this protocol has also been extended to the synthesis of an anti-breast cancer agent and an anticoagulant agent using common feedstock compounds In addition, the postulated mechanism has been explicitly demonstrated via control experiments This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Quality Control of 4,4′-Methylenediphenol).

4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Quality Control of 4,4′-Methylenediphenol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts