A Biochemical Approach for Hedysarum candidissimum from Turkey: Screening Phytochemicals, Evaluation of Biological Activites, and Molecular Docking Study was written by Altay, Ahmet;Yeniceri, Esma;Taslimi, Parham;Taskin-Tok, Tugba;Yilmaz, Mustafa Abdullah;Koksal, Ekrem. And the article was included in Chemistry & Biodiversity in 2022.Electric Literature of C20H22O8 The following contents are mentioned in the article:
This study was designed to screen the phytochem. composition and investigate the biol. activities of Hedysarum candidissimum extracts and also support the results with mol. docking studies. LC/MS/MS anal. revealed the presence of 22 phytochem. constituents (mainly phenolic acids, flavonoids, and flavonoid glycosides) in the plant structure. The methanol extract exhibited the strongest antioxidant activity among all the extracts with its strong DPPH radical scavenging and iron reducing capacity, as well as high phenolic and flavonoid contents. Addnl., it was found to be the most promising acetylcholinesterase (AChE: IC50: 93.26 μg/mL) and α-glycosidase (AG: IC50: 28.57 μg/mL) inhibitory activities, supported by the major phenolics of the species through in silico studies. Et acetate extract had the strongest cytotoxic effect on HT-29 (IC50: 63.03 μg/mL) and MDA-MB-453 (IC50: 95.36 μg/mL) cancer cell lines. Both extracts exhibited considerable apoptotic and anti-migrative effects on HT-29 cells. The investigations provide phyto-anal. and bio-pharmacol. results which can be extended by in vivo studies in the future. This study involved multiple reactions and reactants, such as (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6Electric Literature of C20H22O8).
(2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Electric Literature of C20H22O8
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts