Can polydatin have a beneficial role against bisphenol an exposure in rats? was written by Aslan, Recep;Demirel, Hasan Huseyin;Avdatek, Fatih;Bulbul, Aziz;Eryavuz, Abdullah;Gulay, Mehmet Sukru. And the article was included in Songklanakarin Journal of Science and Technology in 2022.Recommanded Product: 27208-80-6 The following contents are mentioned in the article:
The present study was conducted to evaluate the effects of chronic bisphenol A (BPA) exposure and the possible protective effects of polydatin (PD) on different organs, oxidant-antioxidant status and spermatol. parameters in male Wistar rats. Male Wistar rats (2 to 3 mo old) were randomly divided into 5 groups (n = 6). Group 1 was the control (daily 0.5ml distilled water). Groups 2, 3, 4 and 5 daily received 0.5 mL olive oil (OO), 25 mg/kg bisphenol A in 0.5 olive oil (BPA), 150 mg/kg polydatin (PD), and a mixture of 25 mg/kg bisphenol A in 0.5 olive oil + 150 mg/kg polydatin (BPA-PD), resp., daily for 45 days. BPA had neg. effects on percent abnormal sperm and Hypo-osmotic swelling-Eosin (HE) test (P<0.01). BPA caused neg. histopathol. alterations to the brain, heart, liver, kidney, and testis tissues. PD administration was able to ameliorate the neg. effects of BPA. Moreover, PD had pos. effects on percent motility (P<0.02), head defects of sperm (P<0.01), and HE test (P<0.01) when compared to the controls. The results indicate that PD decreases BPA-induced sperm defects and repaired tissue damage in the various organs in rats. This study involved multiple reactions and reactants, such as (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6Recommanded Product: 27208-80-6).
(2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: 27208-80-6
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts