597-31-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 597-31-9, name is 3-Hydroxy-2,2-dimethylpropanal, molecular formula is C5H10O2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Synthesis of 2,2-dimethyl-3-hydroxypropanal 73.6 g, 2-butyl-2-ethyl-1,3-propanediol 111.8 g, benzene 705g to particulate Nafion (trade name “NR-50”, Sigma-Aldrich put the Ltd.) 3.0 g round bottom flask 2L,while azeotroping with benzene produced water under normal pressure, allowed to react until distillation of water stopped and withdrawn out of the system using a Dean-Stark apparatuss. Filtration, concentrated by vacuum distillation, 2- (5-butyl-5-ethyl-1,3-dioxan-2-yl) -2-methylpropan-1-ol was obtained in a yield of 99%.
The chemical industry reduces the impact on the environment during synthesis 597-31-9, I believe this compound will play a more active role in future production and life.
Reference:
Patent; MITSUBISHI GAS CHEMICAL COMPANY INCORPORATED; IKENO, TAKETO; YOKOBORI, UMI; SATO, HIDEYUKI; TSUJIMOTO, TOMOO; (27 pag.)JP2016/13988; (2016); A;,
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