Effects of consumer products chemicals ingredients and their mixtures on the estrogen receptor/androgen receptor transcriptional activation was written by Lee, Handule;Park, Juyoung;Park, Kwangsik. And the article was included in Chemosphere in 2022.Recommanded Product: 620-92-8 The following contents are mentioned in the article:
Unlike the environmental pollutants or industrial chems., the chems. in consumer products may pose higher levels of risks, depending on how the chems. are used in the products and how humans interact with the products. Recently, endocrine disrupting chems. in cosmetics, personal care products, cleaners, sunscreens, and vinyl products were anal. quantified and many active chems. including phthalates, parabens and bisphenols were detected. This indicates a wide range of exposures from common products. In this study, 35 chems. known to be ingredients of consumer products were selected and screened for the transactivation of estrogen receptors and androgen receptors. From the results of individual chems., the activity of binary/ternary mixture prepared from the agonists for the ER transcription activity was measured, and compared to the predicted values obtained by the full logistic model. The measured and the predicted values were found to be very similar. This study may suggest that prediction of mixture activity by proper models would be one of the supportive tools for the risk assessment and sound regulation of chem. mixtures which have potential endocrine disrupting effects in consumer products. This study involved multiple reactions and reactants, such as 4,4′-Methylenediphenol (cas: 620-92-8Recommanded Product: 620-92-8).
4,4′-Methylenediphenol (cas: 620-92-8) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Recommanded Product: 620-92-8
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts