Adding a certain compound to certain chemical reactions, such as: 616-29-5, 1,3-Diaminopropan-2-ol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Formula: C3H10N2O, blongs to alcohols-buliding-blocks compound. Formula: C3H10N2O
Boc-protected bisamino alcohol 2. A solution of bis-amine 1 (3.00 g, 33.3 mmol) was dissolved in a minimal amount of water (1 mL) and added to a solution of di-tert-butyl dicarbonate (16.0 g, 73.3 mmol) in dioxane (400 mL). The reaction mixture was stirred for 24 hours at room temperature under nitrogen. The solvent was removed under reduced pressure. The resulting solid was dissolved in dichloromethane (300 mL), washed with water (300 mL), dried over MgSO4, and filtered. The solvent was removed under reduced pressure to afford a white solid. The white solid was washed with ether and filtered (9.18 g, 98%). 1H NMR (CDCl3): delta 5.34-5.30 (br, 2NH, 2H), 4.03 (s, 1H, OH), 3.73-3.68 (m, 1H, CH), 3.18-3.14 (m, 4H, 2CH2,), 1.39 (s, 18H, 6CH3). 13C NMR (CDCl3): delta 157.2, 79.71, 70.67, 43.46, 28.39.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,616-29-5, 1,3-Diaminopropan-2-ol, and friends who are interested can also refer to it.
Reference:
Patent; Tew, Gregory; Madkour, Ahmad E.; Lienkamp, Karen; Musante, Ashlan Marie; US2010/317870; (2010); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts