Sing, Nilam et al. published their research in New Journal of Chemistry in 2016 | CAS: 65-22-5

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Quality Control of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

A Co(II) complex of a vitamer of vitamin B6 acts as a sensor for Hg2+ and pH in aqueous media was written by Sing, Nilam;Roy, Sanjay;Guin, Partha Sarathi;Mahali, Kalachand;Majee, Prakash;Mondal, Sudip Kumar;Mahata, Partha;Sengupta, Partha Sarathi;Mondal, Palash. And the article was included in New Journal of Chemistry in 2016.Quality Control of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride The following contents are mentioned in the article:

A Co(II) complex of mol. formula C24H48.4N6O11.2CoCl, 1 CoL2·7.2H2O·Cl, was synthesized from the Schiff base [H2pydmdp]Cl by a template reaction of pyridoxal (pyd), a vitamer of vitamin B6, N-methyl-1,3-diaminopropane (mdp) and cobalt(II) acetate. It was characterized by elemental anal., 1H NMR, IR and UV-visible spectroscopy, thermal anal., electrochem. and single crystal x-ray diffraction. The exptl. results suggested that in complex 1, the central Co(II) is bonded to two phenolato-oxygens, two imine nitrogens and two amine nitrogens in an octahedral geometry. In aqueous media complex 1 exhibits an intense fluorescence emission peak at 506 nm when it was excited at 425 nm. The fluorescence behavior of complex 1 in aqueous media was employed to determine whether it acts as a chemosensor for some selective toxic metal ions. The present complex behaves as a promising sensor for Hg2+ even at the sub-micromolar level. In addition in aqueous solution, complex 1 acts as a sensor for the pH of the medium. A detailed study on the mechanism of sensing behavior established that Hg2+ interacts with complex 1 via weak noncovalent interaction with the N-atom of the pyridine moiety of the mol. The pyridine nitrogen also plays a vital role in sensing the pH of the medium. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Quality Control of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Quality Control of 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts