3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Electric Literature of C8H10ClNO3
Synthesis, X-ray structural features, DFT calculations and fluorescence studies of a new pyridoxal-benzimidazole ligand and its respective molybdenum complex was written by Pereira, Mateus Brum;Kopp, Cristieli R.;Fontana, Liniquer A.;Manzoni de Oliveira, Gelson;Back, Davi Fernando;Piquini, Paulo C.;Villetti, Marcos A.. And the article was included in New Journal of Chemistry in 2014.Electric Literature of C8H10ClNO3 The following contents are mentioned in the article:
Pyridoxal hydrochloride reacts with 1,2-phenylenediamine to give 4-(1H-benzimidazol-2-yl)-5-(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride (BIMIPY, 1). The reaction of 1 with bis(acetylacetonato)-dioxidomolybdenum(VI) leads to the formation of the complex [(MoO2)2(H2O)2(μ-O)(BIMIPY-H+)2]·4DMSO·2H2O (2). In the binuclear complex the metal centers attain a distorted octahedral geometry; a water mol. coordinates to each Mo atom and two imidazolic ligands chelate two MoO2+2 ions. The sixth coordination position in complex 2 is accomplished by a μ-oxido ligand, with an inversion center, which connects two moieties of [(MoO2)(H2O)(BIMIPY-H+)] to a dinuclear species. Secondary, intermol. hydrogen bonds support the growth of the supramol. assembly of the Mo complex. Mechanisms for the formation of the functionalized benzimidazole ligand are also proposed and discussed. First principles DFT calculations of reactivity indexes are used to investigate a possible mechanism leading from the benzimidazole to a dimeric complex involving (MoO2+2) mols. and an oxido bridge ligand. Further, the expected fluorescence of the complex is absent, due to decomposition of the complex in solution On the other hand, an exptl. investigation of the photophys. properties of the ligand shows that it is fluorescent. Time dependent d. functional theory calculations are performed to characterize the absorption and fluorescence spectra of the ligand. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5Electric Literature of C8H10ClNO3).
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Electric Literature of C8H10ClNO3
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts