Application of 597-31-9, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.597-31-9, name is 3-Hydroxy-2,2-dimethylpropanal, molecular formula is C5H10O2, molecular weight is 102.1317, as common compound, the synthetic route is as follows.
2,2-Dimethyl-3-hydroxypropionaldehyde (Hydroxypivalaldehyde, Mitsubishi Gas Chemical Co., Ltd., Purity 99.8%), 59.6 g of 2-ethyl-2-hydroxymethylpropane-1,3-diol (trimethylolpropane, Tokyo Chemical Industry Co., Ltd. reagent), 706 g of benzene, Granular Nafion (trade name “NR-50” Sigma Aldrich Reagent) 5.0 g in a 2-liter round bottom flask, Water generated under atmospheric pressure was withdrawn out of the system using a Dean-Stark trap while azeotropically boiling with benzene, The reaction was allowed to proceed until distillation of water stopped. This was filtered and recrystallized by concentration and cooling, To give crystals of 2- (5-ethyl-5-hydroxymethyl- [1,3] dioxan-2-yl) -2-methylpropan-1-ol.
The chemical industry reduces the impact on the environment during synthesis 597-31-9, I believe this compound will play a more active role in future production and life.
Reference:
Patent; Mitsubishi Gas Chemical Co., Ltd.; Ikeno, Kento; Yokobori, Umi; Sato, Hideyuki; Hasemi, Takashi; (26 pag.)JP2016/84286; (2016); A;,
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