Vojinovic-Jesic, Ljiljana S. et al. published their research in Polyhedron in 2015 | CAS: 65-22-5

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.HPLC of Formula: 65-22-5

Transition metal complexes with thiosemicarbazide-based ligands. Part 63. Syntheses, structures and physicochemical characterization of the first chromium(III) complexes with pyridoxal semi- and thiosemicarbazones was written by Vojinovic-Jesic, Ljiljana S.;Jovanovic, Ljiljana S.;Leovac, Vukadin M.;Radanovic, Mirjana M.;Rodic, Marko V.;Barta Hollo, Berta;Meszasaros Szecsenyi, Katalin;Ivkovic, Sonja A.. And the article was included in Polyhedron in 2015.HPLC of Formula: 65-22-5 The following contents are mentioned in the article:

With pyridoxal semi-/thiosemicarbazones (PLSC/PLTSC) ligands for the first time chromium complexes were obtained. In the reaction of ethanolic solution of Cr(NO3)3 and K3[Cr(NCS)6] and the ligands in mole ratio 1:1 or 1:2, the following complexes were formed: [Cr(PLSC)(PLSC-H)](NO3)2·H2O (1), K[Cr(PLSC-H)(NCS)3]·EtOH (2), [Cr(PLTSC)(PLTSC-H)](NO3)2·2H2O (3), [Cr(PLTSC)2](NO3)3 (4) and [Cr(PLTSC)(NCS)3]·2H2O (5). All the complexes have mer-octahedral structure which in the cases of the complexes 2, 4 and 5 was proved by single-crystal x-ray diffraction anal. The Schiff bases coordinate in the usual tridentate ONX manner (X = O/S; PLSC/PLTSC). The pyridoxalic fragment is Zwitter ion regardless of the form of the coordinated ligands: neutral (keto/thion) and monoanionic (enolic/thiolic). In addition to the above complexes, x-ray crystallog. was used to characterize neutral and protonated forms of PLSC, i.e., PLSC·2H2O and PLSC·HNCS, the latter one being obtained as a byproduct of the reaction of formation of the complex 2 using K3[Cr(NCS)6] and PLSC in the mole ratio 1:2. The x-ray analyses of these ligand forms showed that in the case of PLSC·HNCS the ligation Ophenolic, Nazomethine, Oketo due to strong hydrogen O2-H···N3 bond are placed in cis-position to each other (pro-binding conformation) which is not the case with PLSC·2H2O. The compounds were characterized thoroughly by also IR/UV-visible spectral analyses, electrochem. and thermal methods. This study involved multiple reactions and reactants, such as 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5HPLC of Formula: 65-22-5).

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde hydrochloride (cas: 65-22-5) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.HPLC of Formula: 65-22-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts