A potential species for cosmetic and pharmaceutical industries: Insight to chemical and biological investigation of naturally grown and cultivated Salvia multicaulis Vahl was written by Akdeniz, Mehmet;Yener, Ismail;Yilmaz, Mustafa Abdullah;Irtegun Kandemir, Sevgi;Tekin, Fethullah;Ertas, Abdulselam. And the article was included in Industrial Crops and Products in 2021.COA of Formula: C20H22O8 The following contents are mentioned in the article:
The importance of Salvia L. species, being used as traditional medicine, in the scientific world is increasing day by day. The relationship between health and traditional-modern life, promotes the creation of new value added food products. Within this context, in this study, it was aimed to biol. and chem. investigate the essential oil and ethanol extracts of the Salvia multicaulis Vahl. Chem. and biol. study results of naturally grown and cultivated (uninvestigated in the literature) samples of S. multicaulis were compared. The essential oil, aroma and terpenoid-steroid contents of the species were determined by gas chromatog.-mass spectrometry (GC-MS) and phenolic content by liquid chromatog.-mass spectrometry/mass spectrometry (LC-MS/MS). In addition, the bioactivities of the extracts were screened for antioxidant, cytotoxic, antialzheimer, antiurease, antityrosinase, antielastase and anticollagenase activities. It was found that the enzyme activities of the essential oil and the antioxidant activities of all ethanol extracts of the species were quite high. It was determined that especially essential oil and the ethanol extracts of the leaf parts exhibited high cytotoxic effect in cancer cell lines (PDF (Healthy primary dermal fibroblast cell line), HT-29 (colon cancer cell line), MCF-7 (breast cancer cell line), Caco-2 (colon cancer cell line) and Skov-3 (ovary cancer cell line)). According to the GC-MS results, in the natural specimen 1,8-cineole (33.05 %) and D-limonene (21.18 %), in the cultivated sample 1,8-cineole (42.35 %) and α-pinene (15.74 %) were detected to be as the major components of the essential oil and aroma, resp. It was observed that both natural and cultivated samples were rich in β-Sitosterol. Moreover, the root extract of natural samples was found to be richer than the other extracts in terms of abieatane diterpene (ferruginol, cryptanol, sugiol, and inuroyleanone) compounds According to the LC-MS/MS results, it is seen that both natural and cultivated samples are very rich in rosmarinic acid. Especially, the flower part of the natural sample (98.10 mg analyte/g extract) was found to contain more rosmarinic acid than the other parts. Due to the high total phenolic and rosmarinic acid content, cytotoxic, anti-aging, and antioxidant potential of the ethanol extract of the leaf parts of the species, it has the potential to be used as a food supplement, food preservative and in the pharmaceutical industry. This study involved multiple reactions and reactants, such as (2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6COA of Formula: C20H22O8).
(2S,3R,4S,5S,6R)-2-(3-Hydroxy-5-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (cas: 27208-80-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.COA of Formula: C20H22O8
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts