In 2019,ChemPhysChem included an article by Bouraoui, Amal; Ghanem, Rosy; Berchel, Mathieu; Vie, Veronique; Le Guen, Yann; Paboeuf, Gilles; Deschamps, Laure; Le Gall, Tony; Montier, Tristan; Jaffres, Paul-Alain. HPLC of Formula: 821-41-0. The article was titled 《Bis-thioether-containing lipid chains in cationic amphiphiles cationic amphiphiles: Physicochemical properties and applications in gene delivery》. The information in the text is summarized as follows:
Cationic amphiphiles featuring two thioether functions in each lipid chain of bicatenar cationic amphiphiles are reported here for the first time. The physicochem. properties and transfection abilities of these new amphiphiles were compared with those of already reported analogs featuring either (i) saturated, (ii) unsaturated or (iii) mono-thioether containing lipid chains. The homogeneity of the series of new compounds allowed to clearly underscore the effect of bis-thioether containing lipid chains. This study shows that besides previous strategies based on unsaturation or ramification, the incorporation of two thioether functions per lipid chain constitutes an original complementary alternative to tune the supramol. properties of amphiphilic compounds The potential of this strategy was evaluated in the context of gene delivery and report that two cationic amphiphiles (i. e. 4 a and 4 b) can be proposed as new efficient transfection reagents. The experimental part of the paper was very detailed, including the reaction process of 5-Hexen-1-ol(cas: 821-41-0HPLC of Formula: 821-41-0)
5-Hexen-1-ol(cas: 821-41-0) is a volatile organic compound. Further, it is used to prepare 6-bromo-hex-1-ene by reaction with phosphorus tribromide.HPLC of Formula: 821-41-0
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts