Frost, James R.’s team published research in Tetrahedron in 2021 | CAS: 100-55-0

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cmâˆ?1 (ν19b mode) does not overlap with any of the other bands.Recommanded Product: 100-55-0

Frost, James R.; Cheong, Choon Boon; Akhtar, Wasim M.; Caputo, Dimitri F. J.; Christensen, Kirsten E.; Stevenson, Neil G.; Donohoe, Timothy J. published an article in 2021. The article was titled 《Hydrogen borrowing catalysis using 1° and 2° alcohols: Investigation and scope leading to α and β branched productsã€? and you may find the article in Tetrahedron.Recommanded Product: 100-55-0 The information in the text is summarized as follows:

The alkylation of a variety of ketones, e.g., 1-cyclopropyl-3-(furan-2-yl)propan-1-one using 1° R1OH (R1 = n-Bu, Bn, cyclopropylmethyl, etc.) or 2° alcs. R2R3CHOH (R2 = Me, Et; R3 = Et, Ph, thiophen-2-yl, cyclobutyl, etc.; R2R3 = cyclohexyl, 1,4-dioxaspiro[4.5]decan-8-yl, cyclopentyl, etc.) under hydrogen borrowing catalysis is described. Initial research focused on the α-alkylation of cyclopropyl ketones with higher 1° alcs. (i.e. larger than MeOH), leading to the formation of α-branched products, e.g., 1-cyclopropyl-2-(furan-2-ylmethyl)hexan-1-one. The search for addnl. substrates with which to explore this chem. led to discover that di-ortho-substituted aryl ketones were also privileged scaffolds, with Ph* (C6Me5) ketones being the optimal choice. Further investigations revealed that this motif was crucial for alkylation with 2° alcs. forming β-branched products, which also provided an opportunity to study diastereoselective and intramol. hydrogen borrowing processes. The experimental process involved the reaction of 3-Pyridinemethanol(cas: 100-55-0Recommanded Product: 100-55-0)

3-Pyridinemethanol(cas: 100-55-0) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cmâˆ?1 (ν19b mode) does not overlap with any of the other bands.Recommanded Product: 100-55-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts